Value of SPET/CT image fusion in the assessment of neuroendocrine tumours with 111In-pentetreotide scintigraphy.
Identifieur interne : 007C61 ( Main/Exploration ); précédent : 007C60; suivant : 007C62Value of SPET/CT image fusion in the assessment of neuroendocrine tumours with 111In-pentetreotide scintigraphy.
Auteurs : RBID : pubmed:15701341English descriptors
- KwdEn :
- MESH :
- chemical , analogs & derivatives : Somatostatin.
- chemical , diagnostic use : Indium Radioisotopes, Somatostatin.
- radiography : Neuroendocrine Tumors.
- radionuclide imaging : Neuroendocrine Tumors.
- Adult, Aged, Female, Humans, Male, Middle Aged, Positron-Emission Tomography, Tomography, X-Ray Computed.
Abstract
The purpose of this study was to evaluate the impact and clinical value of anatomical-functional image fusion in the study interpretation and clinical management of patients with neuroendocrine tumours (NET) using somatostatin receptor scintigraphy (SRS) and combined transmission and emission tomography -- single-photon emission tomography/CT (SPET/CT).
PubMed: 15701341
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Value of SPET/CT image fusion in the assessment of neuroendocrine tumours with 111In-pentetreotide scintigraphy.</title><author><name sortKey="Moreira, A Paula" uniqKey="Moreira A">A Paula Moreira</name><affiliation wicri:level="1"><nlm:affiliation>Serviço de Medicina Nuclear, Hospitais da Universidade de Coimbra, Portugal. smnhuc@mail.telepac.pt</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Serviço de Medicina Nuclear, Hospitais da Universidade de Coimbra</wicri:regionArea></affiliation></author><author><name sortKey="Duarte, L Hugo" uniqKey="Duarte L">L Hugo Duarte</name></author><author><name sortKey="Vieira, F" uniqKey="Vieira F">F Vieira</name></author><author><name sortKey="Jo O, F" uniqKey="Jo O F">F João</name></author><author><name sortKey="Lima, J Pedroso De" uniqKey="Lima J">J Pedroso de Lima</name></author></titleStmt><publicationStmt><date when="????"><PubDate><MedlineDate>2005 Jan-Feb</MedlineDate></PubDate></date><idno type="RBID">pubmed:15701341</idno><idno type="pmid">15701341</idno><idno type="wicri:Area/Main/Corpus">002F93</idno><idno type="wicri:Area/Main/Curation">002F93</idno><idno type="wicri:Area/Main/Exploration">007C61</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Humans</term><term>Indium Radioisotopes (diagnostic use)</term><term>Male</term><term>Middle Aged</term><term>Neuroendocrine Tumors (radiography)</term><term>Neuroendocrine Tumors (radionuclide imaging)</term><term>Positron-Emission Tomography</term><term>Somatostatin (analogs & derivatives)</term><term>Somatostatin (diagnostic use)</term><term>Tomography, X-Ray Computed</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Somatostatin</term></keywords><keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Indium Radioisotopes</term><term>Somatostatin</term></keywords><keywords scheme="MESH" qualifier="radiography" xml:lang="en"><term>Neuroendocrine Tumors</term></keywords><keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Neuroendocrine Tumors</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Positron-Emission Tomography</term><term>Tomography, X-Ray Computed</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The purpose of this study was to evaluate the impact and clinical value of anatomical-functional image fusion in the study interpretation and clinical management of patients with neuroendocrine tumours (NET) using somatostatin receptor scintigraphy (SRS) and combined transmission and emission tomography -- single-photon emission tomography/CT (SPET/CT).</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">15701341</PMID><DateCreated><Year>2005</Year><Month>02</Month><Day>09</Day></DateCreated><DateCompleted><Year>2005</Year><Month>07</Month><Day>25</Day></DateCompleted><Article PubModel="Print"><Journal><ISSN IssnType="Print">0212-6982</ISSN><JournalIssue CitedMedium="Print"><Volume>24</Volume><Issue>1</Issue><PubDate><MedlineDate>2005 Jan-Feb</MedlineDate></PubDate></JournalIssue><Title>Revista española de medicina nuclear</Title><ISOAbbreviation>Rev Esp Med Nucl</ISOAbbreviation></Journal><ArticleTitle>Value of SPET/CT image fusion in the assessment of neuroendocrine tumours with 111In-pentetreotide scintigraphy.</ArticleTitle><Pagination><MedlinePgn>14-8</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The purpose of this study was to evaluate the impact and clinical value of anatomical-functional image fusion in the study interpretation and clinical management of patients with neuroendocrine tumours (NET) using somatostatin receptor scintigraphy (SRS) and combined transmission and emission tomography -- single-photon emission tomography/CT (SPET/CT).</AbstractText><AbstractText Label="MATERIAL AND METHODS" NlmCategory="METHODS">Twelve patients (8 female and 4 male; age range 32-74 y, mean 56 y) with proven or clinically suspected NET were studied with routine planar SRS and SPET/CT at 2 and 24 hours after injection of 111-222 MBq 111In-Pentetreotide. Seven patients came for staging/follow-up and 5 patients for primary tumour localization with staging. Analysis of fused images (SPET/CT) was done on a patient basis, with separated evaluation of SPET, low-dose CT images and fusion images. The gold standard for presence or absence of malignancy was pathology or clinical and imaging follow-up data.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">SRS was negative in 6 patients and positive in 6. SPET/CT provided no additional information in 6 patients, including all 6 negative studies. SPET/CT improved localization of SPET detected lesions in 6 positive studies. It defined the extent of the disease and showed bone involvement in 3 of the 6 positive studies. SPET/CT affected the diagnostic interpretation in 6 patients (50 %) and induced changes of management in 3 (25 %).</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The results of this study indicate that combined anatomical-functional imaging with SPET/CT significantly improves tumour localization and characterization, contributing to a better therapeutic management of patients with NET.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Moreira</LastName><ForeName>A Paula</ForeName><Initials>AP</Initials><Affiliation>Serviço de Medicina Nuclear, Hospitais da Universidade de Coimbra, Portugal. smnhuc@mail.telepac.pt</Affiliation></Author><Author ValidYN="Y"><LastName>Duarte</LastName><ForeName>L Hugo</ForeName><Initials>LH</Initials></Author><Author ValidYN="Y"><LastName>Vieira</LastName><ForeName>F</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>João</LastName><ForeName>F</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Lima</LastName><ForeName>J Pedroso de</ForeName><Initials>JP</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType>Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Spain</Country><MedlineTA>Rev Esp Med Nucl</MedlineTA><NlmUniqueID>9208726</NlmUniqueID><ISSNLinking>0212-6982</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Indium Radioisotopes</NameOfSubstance></Chemical><Chemical><RegistryNumber>138661-02-6</RegistryNumber><NameOfSubstance>pentetreotide</NameOfSubstance></Chemical><Chemical><RegistryNumber>51110-01-1</RegistryNumber><NameOfSubstance>Somatostatin</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Indium Radioisotopes</DescriptorName><QualifierName MajorTopicYN="Y">diagnostic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Neuroendocrine Tumors</DescriptorName><QualifierName MajorTopicYN="Y">radiography</QualifierName><QualifierName MajorTopicYN="Y">radionuclide imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y">Positron-Emission Tomography</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Somatostatin</DescriptorName><QualifierName MajorTopicYN="Y">analogs & derivatives</QualifierName><QualifierName MajorTopicYN="Y">diagnostic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y">Tomography, X-Ray Computed</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2005</Year><Month>2</Month><Day>11</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2005</Year><Month>7</Month><Day>26</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2005</Year><Month>2</Month><Day>11</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pii">13070352</ArticleId><ArticleId IdType="pubmed">15701341</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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